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From a medical point of view, these results are of particular significance for the area of treatment of defective T-cell activity. This could offer an opportunity for personalized treatment. In the analysis, the researchers focused on miRNAs: At the end of this process the T-cell is either activated or remains inactive. Statistical cookies Matomo Permit cookies that help us to analyse the page views and user behavior on our websites.

  • Press Release – Helmholtz Zentrum München
  • News and Events — Bernstein Netzwerk Computational Neuroscience
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    Press Release – Helmholtz Zentrum München

    Let us free you from the endless search for suitable IT partners for your international locations and offer you a hand-picked partner network. And we haven't just. Scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München (LMU), members of the German Center for Diabetes.
    Statistical cookies Matomo Permit cookies that help us to analyse the page views and user behavior on our websites.

    This could offer an opportunity for personalized treatment. Necessary cookies Only cookies permitted that are required for the basic functionality of our websites. We use cookies to improve your experience on our Website. Both cells form a characteristic ring-shaped structure at their contact point, the immunological synapse, through which they exchange information.

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    You can personalize your cookie settings here: Cell Reports,DOI: Necessary cookies Only cookies permitted that are required for the basic functionality of our websites.

    To investigate this question, the researchers examined cancer tissues from two independent tissue sample collections: Statistical cookies Matomo Permit cookies that help us to analyse the page views and user behavior on our websites.

    To achieve this, it investigates the interaction of genetics, environmental factors and lifestyle. They organise themselves in small clusters which are transported by actin in the direction of the centre of the synapse.

    As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical.

    News and Events — Bernstein Netzwerk Computational Neuroscience

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    To achieve this, however, immune cells must be able to recognise intruders and to classify them as dangerous or harmless.

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    T-cells red and B-cells blue form immunological synapses at their contact point green. In addition, it is now possible to search for the genes that are influenced by the five miRNAs and find out whether they represent worthwhile target structures for therapy.

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    The T-cell makes contact with the antigen-presenting cell by means of specialized adhesion molecules which initially are randomly distributed over the cell surface.

    The large adhesion molecules accumulate around them in an outer ring. This, however, could not be proved for the other molecules.

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    Where immunological synapses are correctly formed, the receptor molecules are concentrated around a central point whereas the other surface proteins arrange themselves into two rings around this central area.

    Necessary cookies Only cookies permitted that are required for the basic functionality of our websites. The immune system protects the human body against pathogens thus keeping it healthy. To do this, T-cells make contact with the antigen-presenting immune cells and read information from their surface. Functions Print Share on facebook Share on twitter.

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    Where immunological synapses are correctly formed, the receptor molecules are concentrated around a central point whereas the other surface proteins arrange themselves into two rings around this central area. If all the components of the synapse are correctly positioned, activation of the immune cell will result.

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    Imprint De utsch En glish. By using our website, you agree to the use of cookies. From a medical point of view, these results are of particular significance for the area of treatment of defective T-cell activity. These tasks are shared among different cell types:

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    To investigate this question, the researchers examined cancer tissues from two independent tissue sample collections: To achieve this, it investigates the interaction of genetics, environmental factors and lifestyle.

    Functions Print Share on facebook Share on twitter.

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    From a medical point of view, these results are of particular significance for the area of treatment of defective T-cell activity. This could offer an opportunity for personalized treatment. One cause may be human papillomavirus HPVbut the main cause is tobacco smoking and excessive consumption of high-percentage alcohol.

    In the analysis, the researchers focused on miRNAs:

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    1. Contact for the media. To achieve this, however, immune cells must be able to recognise intruders and to classify them as dangerous or harmless.

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    3. From a medical point of view, these results are of particular significance for the area of treatment of defective T-cell activity. They organise themselves in small clusters which are transported by actin in the direction of the centre of the synapse.

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